As part of St. Bonaventure Hospital’s international humanitarian program, the team takes on the case of a young boy from the Congo who has severe congenital heart anomalies. Dr. Neil Melendez has doubts about the safety of the procedure, while Dr. Shaun Murphy works out the best course of action. Meanwhile, Murphy’s latest encounter with his neighbor Lea has him confused.
Dr. Neil Melendez is to operate on a boy, Gabriel, with a heart problem. He does a workup but is adamant that the boy can't be saved. Dr. Marcus Andrews patient, Elizabeth, has surgery to remove a nodule from her vocal cords. Dr. Aaron Glassman worries about Shaun Murphy and insists that he needs outside help. Claire Browne helps Shaun by teaching him about flirting. The lab misplaced Elizabeth's specimen so Claire is assigned to look for it. Dr. Melendez tells Gabriel's mom that they can't operate on her son.
Claire can't find the lost specimen so Jessica Preston comes to tell Elizabeth. Shaun talks to Dr. Glassman about flirting who asks Shaun if he's lonely. Shaun says no that he likes being alone. Gabriel's health deteriorates but that's because his Mom hasn't been giving him his medicine. She is trying to keep him in the hospital until they can cure him. Shaun comes up with the idea to move Gabriel's mitral valve. At first Melendez is against it but is convinced after doing the surgery in virtual reality. Dr. Andrews and his wife get into an argument about Dr. Andrews wanting to become President of the hospital. Elizabeth must choose between having the surgery to remove her voicebox or take the chance and not do anything.
Melendez, Jared Kalu, and Shaun operate on Gabriel. They manage to save him and Melendez tells the Mom. Elizabeth chooses surgery but right before they operate Claire has an epiphany. She finds the specimen in a mislabeled container. Elizabeth is cancer free but decides to sue the hospital so that something like that doesn't happen again. Shaun and Dr. Glassman talk about Shaun getting a life skills coach. Shaun doesn't want one and feels like Dr. Glassman is giving up on him. Shaun attempts to flirt with Lea by dissing her sweater. She invites him into her apartment to have an apple.
- This is the first episode where the title of the episode is based off of something that a character other than Shaun says. (eg Shaun said Oliver in Episode 3, Not Fake in Episode 6, etc.)